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For Fran, Alison, Mark, and Judy

Cover image: Paul Ehrlich’s side chain theory of antibody formation. Note the use of
geometric shapes to indicate different specificities. Antigen selects for the production and
release of the appropriate membrane receptors.

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.I fancy you as coming to the acquisition of the myriad facts of medicine with little to tell
you of the intellectual forces and historical sequences by which these facts have
Christian A. Herter
Imagination and Idealism in Medicine (J. Am. Med. Assoc. 54:423, 1910)

List of plates

Plate 1 Louis Pasteur (1822–1895). Pasteur was honoured at the
Sorbonne at the Jubilee celebration of his seventieth
birthday in 1892


Plate ...
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