Preimplantation Genetic Diagnosis

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Preimplantation Genetic Diagnosis

Preimplantation Genetic
Second Edition
Edited by
Joyce C. Harper


Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo
Cambridge University Press
The Edinburgh Building, Cambridge CB2 8RU, UK
Published in the United States of America by Cambridge University Press, New York

Information on this title: 
© Cambridge University Press 2009
This publication is in copyright. Subject to statutory exception and to the
provision of relevant collective licensing agreements, no reproduction of any part
may take place without the written permission of Cambridge University Press.
First published in print format 2009



eBook (EBL)




Cambridge University Press has no responsibility for the persistence or accuracy
of urls for external or third-party internet websites referred to in this publication,
and does not guarantee that any content on such websites is, or will remain,
accurate or appropriate.
Every eff ort has been made in preparing this publication to provide accurate and
up-to-date information which is in accord with accepted standards and practice at
the time of publication. Although case histories are drawn from actual cases, every
eff ort has been made to disguise the identities of the individuals involved.
Nevertheless, the authors, editors and publishers can make no warranties that the
information contained herein is totally free from error, not least because clinical
standards are constantly changing through research and regulation. The authors,
editors and publishers therefore disclaim all liability for direct or consequential
damages resulting from the use of material contained in this publication. Readers
are strongly advised to pay careful attention to information provided by the
manufacturer of any drugs or equipment that they plan to use.

List of Contributors	


Section 1: Background
  1	 Introduction to preimplantation genetic
diagnosis  1
Joyce C. Harper
  2	 Assisted reproductive technologies  48
Joyce C. Harper, Alpesh Doshi, and Paul Serhal
  3	 Genetic basis of inherited disease  73
Joep Geraedts and Joy Delhanty
  4	 Genetic counseling  85
Alison Lashwood
  5	 Prenatal screening and diagnosis  95
Anna L. David and Charles H. Rodeck
  6	 Preimplantation embryo development  117
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