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Pharmaceutical Process Scale-Up (Michael Levin)

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Pharmaceutical
Process Scale-Up
edited by
Michael Levin
Metropolitan Computing Corporation
East Hanover, New Jersey

Marcel Dekker, Inc.

New York • Basel

TM

Copyright © 2001 by Marcel Dekker, Inc. All Rights Reserved.

ISBN: 0-8247-0625-0
This book is printed on acid-free paper.
Headquarters
Marcel Dekker, Inc.
270 Madison Avenue, New York, NY 10016
tel: 212-696-9000; fax: 212-685-4540
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Marcel Dekker AG
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tel: 41-61-261-8482; fax: 41-61-261-8896
World Wide Web
http://www.dekker.com
The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the headquarters address
above.
Copyright © 2002 by Marcel Dekker, Inc. All Rights Reserved.
Neither this book nor any part may be reproduced or transmitted in any form or by any
means, electronic or mechanical, including photocopying, microfilming, and recording, or
by any information storage and retrieval system, without permission in writing from the
publisher.
Current printing (last digit):
10 9 8 7 6 5 4 3 2 1
PRINTED IN THE UNITED STATES OF AMERICA

DRUGS AND THE PHARMACEUTICAL SCIENCES
Executive Editor

James Swarbrick
PharmaceuTech, Inc.
Pinehurst, North Carolina

Advisory Board
Larry L. Augsburger
University of Maryland
Baltimore, Maryland
Douwe D. Breimer
Gorlaeus Laboratories
Leiden, The Netherlands

David E. Nichols
Purdue University
West Lafayette, Indiana
Stephen G. Schulman
University of Florida
Gainesville, Florida

Trevor M. Jones
The Association of the
British Pharmaceutical Industry
London, United Kingdom

Jerome P. Skelly
Alexandria, Virginia

Hans E. Junginger
Leiden/Amsterdam Center
for Drug Research
Leiden, The Netherlands

Felix Theeuwes
Alza Corporation
Palo Alto, California

Vincent H. L. Lee
University of Southern California
Los Angeles, California

Geoffrey T. Tucker
University of Sheffield
Royal Hallamshire Hospital
Sheffield, United Kingdom

Peter G. Welling
Institut de Recherche Jouveinal
Fresnes, France

DRUGS AND THE PHARMACEUTICAL SCIENCES
A Series of Textbooks and Monographs

1. Pharmacokinetics, Milo Gibaldi and Donald Perrier
2. Good Manufacturing Practices for Pharmaceuticals: A Plan for Total
Quality Control, Sidney H. Willig, Murray M. Tuckerman, and William
S. Hitchings IV
3. Microencapsulation, edited by J. R. Nixon
4. Drug Metabolism: Chemical and Biochemical Aspects, Bernard Testa
and Peter Jenner
5. New...
Marcel Dekker, Inc. New York
Basel
TM
Pharmaceutical
Process Scale-Up
edited by
Michael Levin
Metropolitan Computing Corporation
East Hanover, New Jersey
Copyright © 2001 by Marcel Dekker, Inc. All Rights Reserved.
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